This laboratory is a joint NHS/ Academic Department of Clinical Biochemistry at Addenbrooke’s Hospital, where it provides a full Clinical Biochemistry service to the hospital, and is part of the Cambridge University Clinical School. The NHS Department of Clinical Biochemistry at Addenbrooke’s has held full UKAS accreditation since 2017 and provides three services for the SAS:
Referred thyroid function tests. The department provides a comprehensive suite of biochemical and genetic tests for the investigation of unusual thyroid function tests including thyroid hormone resistance, familial dysalbuminaemic hyperthyroximaemia, ‘macro-TSH’, and anti-thyroid antibodies. New results are reviewed at a weekly MDT meeting so appropriate clinical advice can be provided. Please contact the the pathology help desk for further information and to request the specific request card required.
Severe insulin resistance. We provide an integrated clinical, biochemical, immunological and genetic service for patients with severe IR and support the NHS Severe Insulin Resistance Service. We have expertise in identifying and characterising both genetic and acquired, immunologically-mediated forms of severe IR and LD, and have developed diagnostic algorithms incorporating biochemical triage and genetic testing. We are able to provide advice on both diagnosis and management, and written patient information literature. Clinical discussion prior to targeted testing is strongly recommended to ensure the highest diagnostic yield
Investigation of macrohormones – we offer specialised analysis where appropriate for the investigation of hormone:immunoglobulin complexes, particularly macroprolactin and macro-TSH.