Research at the Rosie

We undertake studies related to women’s reproductive health, pregnancy, labour and newborn babies’ health and wellbeing.

The Rosie hospital works closely with the medical school of the University of Cambridge. We are often involved in research. If you are approached to be involved in collection of data etc, we hope that you will give it your full consideration, and your written permission will always be sought. If you decline to be included, it will in no way affect your care or treatment. At all stages you will be able to discuss your care with your midwife. Please do not hesitate to ask questions, if you do not fully understand what is being discussed.

The Rosie Hospital undertakes research related to women’s reproductive health, pregnancy, labour and newborn babies’ health and wellbeing. Research is important because it helps to improve your healthcare by finding out which treatment work best and why, so that there are ever better outcomes for mothers and babies. We all benefit at some stage in our lives from care or treatment that has in some way been developed and improved thanks to research. For up to date information on research being done at The Rosie please check the noticeboard situated in the corridor leading to the Ultrasound Department.

Patients

Patients are very important in designing and improving future research. Your midwife, doctor or nurse might talk to you about taking part in a clinical research study as part of your care, but you can also ask them about clinical studies that might be suitable for you. If you are approached to be involved in collection of data etc, we hope that you will give it your full consideration, and your written permission will always be sought. If you decline to be included, it will in no way affect your care or treatment. At all stages you will be able to discuss your care with your midwife. Please do not hesitate to ask questions, if you do not fully understand what is being discussed.

How can you find out more

Patients are very important in designing and improving future research. Your midwife, doctor or nurse might talk to you about taking part in a clinical research study as part of your care, but you can also ask them about clinical studies that might be suitable for you.  Some studies currently being done at The Rosie are listed below but more are always starting, so do contact us if you would like to find out more, by emailing our Research Midwife.

Elena Romero
Senior Research Midwife
Phone: 01223 274 228
Email: elena.romero@addenbrookes.nhs.uk

Studies

POPS2

Are you currently less than four months pregnant with your first baby? If so, please read on.

We are conducting a research study where we perform extra scans at 28 and 36 weeks. We are looking for women, pregnant with their first baby, who are interested in taking part.

You can find out more about the study from the Participant Information Leaflet which is available at https://www.obgyn.cam.ac.uk

Alternatively, you can obtain the leaflet by email (pops2@addenbrookes.nhs.uk) or write to us at the Department of Obstetrics and Gynaecology, Cambridge University, Box 223 The Rosie Hospital, Robinson Way, Cambridge, CB2 0SW, UK.

If after reading the leaflet you think you might be interested in taking part, please get in touch using the contact details on the last page.  We can then arrange for you to see a member of our research team to chat it over and answer any questions, before giving your consent.

DiGest

Participate in a research study about nutrition in gestational diabetes. We are running a research study to assess the best diet for women with gestational diabetes. This study will test two diets with different total calorie intake to identify which is healthiest for mums and babies.

Contact details: add-tr.digeststudy@nhs.net

GEM3

To assess the effectiveness of a combination of methotrexate and gefitinib against methotrexate alone in terms of the need for surgical intervention for ectopic pregnancy.

GHIP (Gut Hormones in Pregnancy)

The GHIP study Team are looking for women with a viable pregnancy on scan dating them between 7+0 and 11+0 weeks to donate a one off blood sample. The samples will be used to compare the gut hormones of women with Hyperemesis to samples from pregnant women with little or no nausea.

SUPPORT

Researchers supported by Tommy’s are comparing three ways of treating a short cervix during pregnancy to help stop babies being born too early.

Cleft Collective

The Cleft Collective cohort studies will investigate the biological and environmental causes of cleft, the best treatments for cleft and the psychological impact of cleft on those affected and their families.

ALIFE-2

ALIFE 2 is a multi-centre randomised clinical trial to compare Low Molecular Weight Heparin (LMWH) with standard pregnancy surveillance in women with inherited thrombophilia (a blood clotting problem) and a history of recurrent miscarriage (RM).

Women with a history of RM (2 or more not necessarily consecutive miscarriages or intra-uterine foetal deaths), confirmed inherited thrombophilia and who are attempting to conceive or are less than 7 weeks pregnant (based on first day of last menstruation) will be registered onto the study. Participants will be randomised to one of two groups.

Participants in group 1 will inject LMWH once daily, starting immediately after randomisation. LMWH will be discontinued at the beginning of labour.

TOPSY

This study aims to assess if self-management of pelvic organ prolapse using a vaginal pessary is more effective at improving women’s quality of life than standard follow up care. Women with any severity or kind of prolapse will be invited to take part in the study.

CRAFT

This study aims to investigate whether a cervical stitch in women who have a short cervix following a full dilatation in a previous pregnancy is a good treatment in reducing early delivery of their babies (preterm babies).

LIPID

There is clear evidence that early nutrition is an important modifier of long-term health outcomes in preterm babies. This study aims to explore the impact of prematurity on lipid profiles in the neonatal period.

PAN-COVID

PAN-COVID study is a global registry of women with suspected COVID-19 or confirmed SARS-CoV-2 infection in pregnancy and their neonates. It is an observational study aiming to understand the natural history of COVID-19 in pregnancy, in order to guide treatment and prevention during the outbreak.

For more information: https://pan-covid.org/

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