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Research at the Rosie

We undertake research related to women’s reproductive health, pregnancy, labour and newborn babies’ health and wellbeing.

The Rosie Hospital undertakes research related to women’s reproductive health, pregnancy, labour and newborn babies’ health and wellbeing. CUH has a proud history of medical research and The Rosie hospital also works closely with the medical school of the University of Cambridge. Research is important because it helps to improve your healthcare by finding out which treatment work best and why, so that there are ever better outcomes for mothers and babies. Without people volunteering to take part in research, we would not be able to improve and develop the care or treatment that we offer.

Taking part

Your midwife, doctor or nurse might talk to you about taking part in a clinical research study as part of your care and we hope that you will give it your full consideration. If you decline to be included, it will in no way affect your care or treatment and at all stages you will be able to discuss your care with your midwife or doctor. Please do not hesitate to ask questions, if you do not fully understand what is being discussed.

How can you find out more

You can ask your health professional about clinical studies that might be suitable for you. Some studies currently being done at The Rosie are listed below but more are always starting, so do contact us if you would like to find out more, by emailing our Rosie Research Team.

If you are interested in taking part in a research study at The Rosie, please have a look at the information below to find a study that is right for you or you can also check the noticeboard situated in the corridor leading to the Ultrasound Department. You contact the research team directly using the details below.

Phone: 01223 274 228



Cleft Collective

The Cleft Collective cohort studies will investigate the biological and environmental causes of cleft, the best treatments for cleft and the psychological impact of cleft on those affected and their families.


This study aims to investigate whether a cervical stitch in women who have a short cervix following a full dilatation in a previous pregnancy is a good treatment in reducing early delivery of their babies (preterm babies).


Sometimes the neck of the womb can start to open early. If this happens too early in pregnancy (before 28 weeks), there are a limited number of treatment options. The aim of this study is to find out what treatment, in the event of this happening, is best and safe for mothers and babies.


Participate in a research study about nutrition in gestational diabetes. We are running a research study to assess the best diet for women with gestational diabetes. This study will test two diets with different total calorie intake to identify which is healthiest for mums and babies.

Contact details:


Until recently the standard test for gestational diabetes Mellitus (GDM; the most common form of diabetes in pregnancy) was the Oral Glucose Tolerance Test (OGTT). However, due to Covid-19, many hospitals have had to change the diagnostic pathway, in order to adapt to new social distancing recommendations. There is now a combination of methods being used to diagnose gestational diabetes but this has not been thoroughly tested.

The aim of the study is to investigate whether the new diagnostic strategy can correctly identify women with high blood glucose levels in pregnancy.


Women with antiphospholipid antibodies may have an increased risk of having blood clots and pregnancy problems because blood becomes more ‘sticky’ than usual. The purpose of the Study is to answer the question as to whether hydroxychloroquine may help improve pregnancies in women with antiphospholipid antibodies.


There is clear evidence that early nutrition is an important modifier of long-term health outcomes in preterm babies. This study aims to explore the impact of prematurity on lipid profiles in the neonatal period.


The LOCI trial studies which treatment is best for ovulation induction and a successful pregnancy outcome in women diagnosed with polycystic ovary syndrome (PCOS).


Obstetric anal sphincter injury (OASI) is the combined term for severe perineal tears that can occur during childbirth. Severe tears can have a long-term impact on women’s wellbeing. The Rosie has adopted the OASI Care Bundle, which is a standardised set of evidence-based practices aimed at reducing rates of perineal tears and the OASI2 project studies the implementation of this bundle.

PIPKIN: Perinatal Imaging Partnership with Families

The PIPKIN project tracks babies development from the third trimester of pregnancy to the first few months of family life, with the aim of understanding how infant brain responses are shaped by social interactions and the environment around the child. We are interested in how variability emerges in individual infants, and how diversity of experience and social norms influence babies' brains and behavior.

Our study involves combining methods parents might use to document their babies health and milestones (diaries, videos and questions) with measures used by researchers to record infant neural and behavioural activity. Participating families visit the Rosie Hospital at Addenbrooke's for an ultrasound to study the baby in the womb; after birth, researchers visit the family at home, using mobile, safe equipment to image the baby's brain, such as Functional Near Infrared Spectroscopy (fNIRS) and Electroencephalography (EEG). A final visit takes place at the Cambridge Babylab when infants are five months old.

The project is seeking infants from a range of backgrounds, with the goal of designing family-friendly perinatal interventions in partnership with parents, community NCT groups and clinicians. We hope to use what we learn from this project to support caregivers and babies, so families from every walk of life have the best possible opportunity to develop their full potential.

For more information on the study, please visit Home | Pipkin (

If you are expecting or have a young baby and would like to learn more or take part in the PIPKIN study, please send an email to or register your pregnancy or baby:


Are you currently less than four months pregnant with your first baby? If so, please read on.

We are conducting a research study where we perform extra scans at 28 and 36 weeks. We are looking for women, pregnant with their first baby, who are interested in taking part.

You can find out more about the study from the Participant Information Leaflet which is available at

Alternatively, you can obtain the leaflet by email ( or write to us at the Department of Obstetrics and Gynaecology, Cambridge University, Box 223 The Rosie Hospital, Robinson Way, Cambridge, CB2 0SW, UK.

If after reading the leaflet you think you might be interested in taking part, please get in touch using the contact details provided. We can then arrange for you to see a member of our research team to chat it over and answer any questions, before giving your consent. You can also call the number below and leave a message if you are interested in participating in the study.

Phone: 01223 769262


At the end of labour, most babies have rotated round in their mother’s pelvis so that the back of their head (the occiput) is at the front of the pelvis. Some babies end up in a different position that might make it more difficult for mum. The ROTATE study is investigating how best to get babies into a good position for a vaginal birth if problems arise at the end of labour.

The CERM trial

The aim of this research trial is to find out if antibiotics can reduce miscarriage in women with endometritis (inflammation of the lining of the womb, the endometrium). A healthy endometrium is important for the embryo to be able to attach to the womb. It is thought that endometritis disrupts this process, and can lead to a miscarriage. Treating endometritis with antibiotics may reduce the inflammation and the likelihood of a miscarriage. This research trial will test this theory by comparing a 14-day course of an antibiotic against a placebo.


The Rainbow Clinic provides specialist care and support to families who have experienced the death of a baby during pregnancy or shortly afterwards. As this is a new clinical service in most hospitals we would like to evaluate the care provided in the clinics across the United Kingdom, to look at where care can be improved; your experiences will help to do this.


Researchers supported by Tommy’s are comparing three ways of treating a short cervix during pregnancy to help stop babies being born too early.

Participate to Rosie trials

To find out more about participating in the trials available to women and babies at the Rosie or to ask for further information, please contact the research team directly using the details provided.

University of Cambridge Department of Paediatrics