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Research at the Rosie

We undertake research related to women’s reproductive health, pregnancy, labour and newborn babies’ health and wellbeing.

The Rosie Hospital undertakes research related to women’s reproductive health, pregnancy, labour and newborn babies’ health and wellbeing. CUH has a proud history of medical research and The Rosie hospital also works closely with the medical school of the University of Cambridge. Research is important because it helps to improve your healthcare by finding out which treatment work best and why, so that there are ever better outcomes for mothers and babies. Without people volunteering to take part in research, we would not be able to improve and develop the care or treatment that we offer.

Taking part

Your midwife, doctor or nurse might talk to you about taking part in a clinical research study as part of your care and we hope that you will give it your full consideration. If you decline to be included, it will in no way affect your care or treatment and at all stages you will be able to discuss your care with your midwife or doctor. Please do not hesitate to ask questions, if you do not fully understand what is being discussed.

How can you find out more

You can ask your health professional about clinical studies that might be suitable for you. Some studies currently being done at The Rosie are listed below but more are always starting, so do contact us if you would like to find out more, by emailing our Rosie Research Team.

If you are interested in taking part in a research study at The Rosie, please have a look at the information below to find a study that is right for you or you can also check the noticeboard situated in the corridor leading to the Ultrasound Department. You contact the research team directly using the details below.

Phone: 01223 274 228

Email: RosieResearch@addenbrookes.nhs.uk

Studies

POPS2

Are you currently less than four months pregnant with your first baby? If so, please read on.

We are conducting a research study where we perform extra scans at 28 and 36 weeks. We are looking for women, pregnant with their first baby, who are interested in taking part.

You can find out more about the study from the Participant Information Leaflet which is available at https://www.obgyn.cam.ac.uk

Alternatively, you can obtain the leaflet by email (pops2@addenbrookes.nhs.uk) or write to us at the Department of Obstetrics and Gynaecology, Cambridge University, Box 223 The Rosie Hospital, Robinson Way, Cambridge, CB2 0SW, UK.

If after reading the leaflet you think you might be interested in taking part, please get in touch using the contact details provided. We can then arrange for you to see a member of our research team to chat it over and answer any questions, before giving your consent. You can also call the number below and leave a message if you are interested in participating in the study.

Phone: 01223769262

DiGest

Participate in a research study about nutrition in gestational diabetes. We are running a research study to assess the best diet for women with gestational diabetes. This study will test two diets with different total calorie intake to identify which is healthiest for mums and babies.

Contact details: add-tr.digeststudy@nhs.net

Gest-test

Until recently the standard test for gestational diabetes Mellitus (GDM; the most common form of diabetes in pregnancy) was the Oral Glucose Tolerance Test (OGTT). However, due to Covid-19, many hospitals have had to change the diagnostic pathway, in order to adapt to new social distancing recommendations. There is now a combination of methods being used to diagnose gestational diabetes but this has not been thoroughly tested.

The aim of the study is to investigate whether the new diagnostic strategy can correctly identify women with high blood glucose levels in pregnancy.

HYPATIA

Women with antiphospholipid antibodies may have an increased risk of having blood clots and pregnancy problems because blood becomes more ‘sticky’ than usual. The purpose of the Study is to answer the question as to whether hydroxychloroquine may help improve pregnancies in women with antiphospholipid antibodies.

GEM3

To assess the effectiveness of a combination of methotrexate and gefitinib against methotrexate alone in terms of the need for surgical intervention for ectopic pregnancy.

SUPPORT

Researchers supported by Tommy’s are comparing three ways of treating a short cervix during pregnancy to help stop babies being born too early.

Cleft Collective

The Cleft Collective cohort studies will investigate the biological and environmental causes of cleft, the best treatments for cleft and the psychological impact of cleft on those affected and their families.

CRAFT

This study aims to investigate whether a cervical stitch in women who have a short cervix following a full dilatation in a previous pregnancy is a good treatment in reducing early delivery of their babies (preterm babies).

LIPID

There is clear evidence that early nutrition is an important modifier of long-term health outcomes in preterm babies. This study aims to explore the impact of prematurity on lipid profiles in the neonatal period.

PAN-COVID

PAN-COVID study is a global registry of women with suspected COVID-19 or confirmed SARS-CoV-2 infection in pregnancy and their neonates. It is an observational study aiming to understand the natural history of COVID-19 in pregnancy, in order to guide treatment and prevention during the outbreak.

For more information: https://pan-covid.org/

Additional links

To find out more about participating in the trials available to women and babies at the Rosie or to ask for further information, please contact the research team directly using the details provided.

University of Cambridge Department of Paediatrics