Renal genetics and tubular disorders

This clinic is for patients with kidney disorders that are known to be inherited or that often run in families.
Telephone: 
01223 256318

This clinic is for patients with kidney disorders that known to be inherited or that often run in families. It brings together staff from Addenbrooke’s Hospital:

Nephrology, medical genetics, urology and clinical biochemistry, to see patients whose disease usually needs to be looked after by one or more of these specialties.

It is located in Clinic 33 on Level 3 of the Addenbrooke's Treatment Centre.

Patients may be referred by their general practitioners (GPs) or by hospital doctors from Addenbrooke’s, from local hospitals or from further away if there is no local centre.

Telephone enquiries: 01223 217828

Clinic reception: 01223 348506

What does the clinic offer?

At each clinic there is one or more of a consultant nephrologist, medical geneticist, urologist and chemical pathologist, and a specialist renal nurse responisble for our Tolvaptan

programme for PKD patients.

We have the expertise in the clinic at a single visit to evaluate fully and care for the patient, which should lead to better and more efficient care.

We have access to genetic counselling and can arrange diagnostic mutation screening for selected conditions where the causative gene is known.

Referral information

Which patients are referred to us?

We can provide services to:

  • Adults who have all types of renal tubular diseases including polycystic kidney disease; the cause may be acquired, hereditary or unknown.
  • Patients who have recurrent kidney stones and/or a family history of kidney stones.

We are also happy to see ‘at-risk’ relatives of patients.

Typical diagnoses or problems include:

  • Autosomal dominant polycystic kidney disease (ADPKD)
  • Bartter Syndrome
  • Cystinuria
  • Dent disease
  • Familial hypertension
  • Gitelman syndrome
  • Hypercalciuria (of unknown cause)
  • Hypomagnesemia (of unknown cause)
  • Hypophosphatemia
  • Medullary cystic kidney disease
  • Nephrocalcinosis and medullary sponge kidney
  • Nephronophthisis
  • Recurrent hypokalaemia or hyperkalaemia (of unknown cause)
  • Recurrent kidney stones
  • Renal tubular acidosis (definite or possible)
  • Severe gout with renal impairment
  • And other rare syndromes affecting the kidney

For referring doctors:

To make referrals, please use EPIC specifying 'RGTD clinic' (and FAO Professor Fiona Karet) or contact:

The Clinic PA, RGTD Clinic, Box 118, Addenbrooke’s Hospital, Hills Road, Cambridge CB2 0QQ

Telephone: 01223 217828

Fax: 01223 586506