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Patient information on Ultrasound guided foam sclerotherapy for the treatment of varicose veins (in the leg)

Patient information A-Z

Who this leaflet is for and what is its aim?

This leaflet is for patients who have been diagnosed with varicose veins and have been recommended to have ultrasound guided foam sclerotherapy.

This leaflet aims to explain the procedure and its risks.

Background Information

Varicose veins are very common, affecting at least 20-40% of the adult population in the UK. This condition can be painful and in certain cases if untreated, can lead to leg swelling, pigmentation of the skin of the lower leg, and ulcers. There are a number of ways that varicose veins can be treated – endothermal treatment, sclerotherapy, open surgery and conservative treatment.

You have been recommended to have open surgery to remove these varicose veins. It is assumed that you have had a conversation about the suitability of these different techniques of treating your veins in the clinic with the vascular surgery team in charge of your care (see below).

The great saphenous vein starts at the ankle, runs underneath the skin of the calf and thigh, and ends in the groin. In the groin, the great saphenous vein connects with the femoral vein (in the deep system of veins).

The small saphenous vein starts at the back of the foot, runs underneath the skin of the calf, ending behind the knee (at a variable level). Behind the knee, the vein connects with the popliteal vein (in the deep system of veins).

Veins in the legs drain blood from the foot back to the heart. This is driven by your muscles pumping the blood up against gravity, and the veins have delicate one-way valves that prevent blood flowing back to the foot.

In varicose veins these valves become incompetent, and blood flows back to the foot leading to higher vein pressure and the signs and symptoms of varicose veins.

The Procedure

Sclerotherapy or injection of varicose veins is a procedure designed to close your varicose veins in order to prevent further damage to your skin and hopefully avoid ulceration. It may also improve the swelling or discomfort associated with varicose veins.

If you have an ulcer, this treatment may speed up the healing process and will reduce the risk of the ulcer returning by around 50%.

The veins are injected with a solution called a sclerosant which damages the internal lining of the vein and “sclerosis” and inflammation of the vein. In time your own body will then destroy the vein and it will disappear. The solution normally used for this procedure is called sodium tetradecyl sulphate (STS), which is a detergent and is available in different concentrations depending on the size of the vein being treated. The sclerosant is mixed with air to create a foam which helps it be more effective.

Are my veins suitable for foam injection sclerotherapy?

Most patients with varicose veins are potentially suitable for this form of treatment. If you have very extensive and very large varicose veins then other treatments may be preferable to sclerotherapy. Your surgeon will advise you on this. If you have any underlying blood clotting tendency it may not be advisable to have sclerotherapy.

Before your procedure

On the day of your treatment you will attend clinic. The date and time will be confirmed with you. Please eat and drink as normal before the procedure – this helps the veins fill as much as possible. The whole process will take around 30 minutes but occasionally longer. In addition, because treatments can be unpredictable, there may be a wait of an hour or so before your treatment

Should I continue my normal medication before treatment?

This depends on your own situation. We would normally advise you to stop taking the combined oral contraceptive pill or hormone replacement therapy tablets one month before the foam sclerotherapy treatment. This is to reduce the risk of deep vein thrombosis (DVT), which can be increased if you are taking medicines containing the hormone oestrogen.

Please inform your doctor at the hospital if you are taking warfarin, apixaban, edoxaban or rivaroxaban or similar blood thinning medication, as sometimes this may need to be stopped before your procedure though this is rare.

During your procedure

Depending on the number of varicose veins you have, you may need one or two sessions of treatment and, very occasionally, more than this. The main surface vein to be treated will be checked initially, using ultrasound scanning.

A needle will be placed into the vein, again using ultrasound scanning. This will be flushed with a salt solution to keep the needle open. Typically, a further two or three small needles (alled butterfly needles) will then be inserted into the varicose veins in the leg and these will be similarly flushed.

Your leg will then be elevated by tipping up the couch you are lying on and the foam solution will be injected in small volumes via each of the needles. You may experience some slight stinging as the foam is injected but it is usually painless.

The passage of the foam in the vein will be monitored by ultrasound scanning and the foam injections into each needle may need to be repeated two or three times.

Once enough foam has been injected the needles will be removed, pieces of gauze will be applied to your leg initially. The surgeon may then choose to apply a compression stocking or a bandage, in order to compress the treated veins. This will feel tight but will not be so tight as to make your foot discoloured, painful or lose sensation. If this does occur, please remove the bandage and the stocking. The stocking or bandage act to reduce pain after treatment rather than affect how well the treatment works.

Getting about after the procedure

Once your procedure is completed you will be able to walk back to the waiting area. You should stay in the waiting area for around 15 minutes, after which you can go home.

Leaving hospital

The operation is usually performed as a day case. You should be able to walk in and out of the treatment room without significant issues.

Resuming normal activities including work

If you normally drive, you may find it difficult to drive home with your stocking and bandages on and so should arrange for someone to accompany you.

You should do plenty of walking and generally may do most normal activities without any problem.

We would advise that you do not plan any long-haul flights (three hours) within six weeks of your treatment (to minimise the risk of DVT). If in doubt, ask your treating team at the hospital. We will send your GP a letter about the treatment you have undergone.

Special measures after the procedure

Self-adherent compression bandages, or non-adherent crepe bandages, can be removed usually after 24 hours (this will be guided by the surgeon performing the procedure).

Once the bandages are removed, you may be given a pair of compression stockings to wear for a week, or until the legs feel comfortable. The purpose of the stockings is to support the leg, to help blood flow through the deep veins of the leg and to reduce the amount of bruising and tenderness.

At night, the stockings can be removed if this is more comfortable.

If you are still concerned, please call the daytime number for the hospital given to you on the information sheet, the Cambridge Vascular Unit Vascular Specialist Nurses, or you can call your GP.

Intended Benefits

To prevent further damage to your skin and hopefully avoid ulceration. It may also improve the swelling or discomfort associated with varicose veins.

Risks

Superficial thrombophlebitis / Superficial Venous Thrombosis

Most people will experience some hard lumps which form in the treated veins. These are areas of blood clotting in the treated veins. This is nothing to worry about but may be associated with inflammation (redness) and discomfort. If this occurs, anti-inflammatory pain killers, such as ibuprofen, may help. These lumps will eventually subside and disappear but this may take several weeks or months.

Brown pigmentation of the skin

This can occur following superficial thrombophlebitis described above and can be quite extensive. Approximately 1 in 3 people will develop it to a greater or lesser extent. In about 1 case in 5 this can be permanent and obvious. However, it will usually fade for a period of several months and may disappear completely.

Deep venous thrombosis

If the solution passes into the deep veins there is a risk of thrombosis of the deep veins. A thrombosis such as this occurs once every 100-150 procedures. This may be very minor with no symptoms or a major blood clot with a risk of a pulmonary embolus (passage of a blood clot to the lungs). It is for this reason that only small volumes of the foam are injected at a time and the ankle is exercised in order to maintain good flow in the deep veins. Surgery itself also carries a risk of deep vein thrombosis. You may be offered an injection at the end of the procedure to reduce the risk of this or be offered extended prophylaxis for a few days.

Recurrent and residual varicose veins

It is possible that the treated vein could reopen. The risk of this is around 20-25%. If this does happen, it may be possible to treat the vein again, either by further injection or by surgery. It may not cause any symptoms or problems and if not we would not advocate further intervention.

Not every vein will be treated and sometimes residual veins are left after the procedure.

Skin Ulceration

If the solution does not go into the vein but goes into the surrounding tissues, it can rarely cause a small ulcer of the skin. This will usually heal up but it may take several weeks and will leave a scar.

Allergic Reaction

Allergy to the solution used is rare but can occur. If you have any allergies, you should inform your doctor.

Visual Disturbance

There are reports of temporary visual disturbance and chest pain with foam injections. This is thought to be due to the air bubbles rather than the solution injected and occurs in about 1 in 667 to 1 in 833 patients.

Migraine

If you suffer with migraines then please inform the surgeon, as it is not uncommon to experience a migraine after injection. An alternative treatment may be considered especially if you take medications for migraine prevention regularly. This occurs in 1 in 500 to 1 in 800.

Stroke

In the published medical literature, there have been a very tiny number of strokes reported after foam sclerotherapy. In the past larger volumes of foam were used, and ultrasound was not fully utilised to control where the foam travelled to. However, as time has progressed surgeons have taken steps to control the factors that place patients at risk of a stroke. The current risk of stroke is less than 1:6000.

Death

A severe allergic reaction or a large pulmonary embolus or stroke may result in death. Whilst this is very unlikely it is something you should be aware of.

Alternatives

Foam sclerotherapy has been in widespread use in the NHS for at least 20 years. The National Institute for Clinical Excellence (NICE), now recommend the use of foam sclerotherapy before surgery is considered. Some techniques are better suited for some types of veins than others, and your surgeon will have weighed up the benefits of other treatments in your case.

The alternative treatments include heating and sealing the vein under local anaesthetic (also called endothermal ablation, laser ablation, radiofrequency or VNUS ablation, or sealing the vein using medical glue) or surgery (saphenous vein stripping and avulsions). Occasionally, patients are suitable for one or more of these, but there is often one treatment that will suit your particular vein type more than the others.

If you think you want to consider one of the other therapies, please contact the Vascular Surgery team before your day of treatment as it is often not possible to switch treatments on the day planned for your operation

Medication

Bring all of your medicines (including inhalers, injections, creams, eye drops or patches) and a current repeat prescription from your GP

Please tell the ward staff about all of the medicines you use. During your stay If you wish to take your medication yourself (self-medicate) please speak with your nurse. Pharmacists visit the wards regularly and can help with any medicine queries.

My Chart

We would encourage you to sign up for MyChart. This is the electronic patient portal at Cambridge University Hospitals that enables patients to securely access parts of their health record held within the hospital’s electronic patient record system (Epic). It is available via your home computer or mobile device

More information is available on our website: MyChart

Contacts

Do feel free to contact the Cambridge Vascular Unit Specialist Nurses on 01223 348526 or Email Cambridge Vascular Unit if you have any questions or anxieties.

Sources of evidence

We are smoke-free

Smoking is not allowed anywhere on the hospital campus. For advice and support in quitting, contact your GP or the free NHS stop smoking helpline on 0800 169 0 169.

Other formats

Help accessing this information in other formats is available. To find out more about the services we provide, please visit our patient information help page (see link below) or telephone 01223 256998. www.cuh.nhs.uk/contact-us/accessible-information/

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Cambridge University Hospitals
NHS Foundation Trust
Hills Road, Cambridge
CB2 0QQ

Telephone +44 (0)1223 245151
https://www.cuh.nhs.uk/contact-us/contact-enquiries/