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Dr Michalis Kostapanos

Consultant physician and affiliated assistant professor

I am a consultant in acute and general internal medicine, lipidologist and principal investigator in early phase clinical trials.
Dr Michalis Kostapanos

My current role

Clinical

I am a Consultant in Acute and General Internal Medicine. I specialise in Dyslipidaemias, Hypertension, and high heart risk. I also work in the Lipid and Hypertension clinics at Addenbrooke's Hospital.

Research

I am an MHRA-approved Principal Investigator for Phase 1 Clinical Trials, including First in Human studies. I lead these trials and experimental medicine studies at the GSK Phase 1 Clinical Unit in Cambridge. I have also been a PI and sub-investigator in trials run by Cambridge University Hospitals and the University of Cambridge.

Teaching

I am an Undergraduate Specialty Tutor at the Cambridge University School of Clinical Medicine.

I focus on Acute Internal Medicine at Addenbrooke's Hospital. I also supervise student placements in Acute Internal Medicine and Clinical Pharmacology.

Previous history

I graduated from the University of Ioannina Medical School, Greece in 2004. I completed my PhD in Medicine there in 2014. I finished my Specialty training in Internal Medicine at the University Hospital of Ioannina in 2013 (CCT in General Internal Medicine).

Since 2005, I have been an active clinical researcher. I have worked as an Investigator in many clinical trials. I have designed studies in Atherosclerosis prevention, Cardiovascular Pharmacology, and Dyslipidaemias. I have continued this work during my PhD, specialty training, and as a Consultant.

Alongside research, I have worked clinically:

  1. As a Clinical Fellow (pre-CCT) in the Lipids and Cardiovascular Risk clinic at the University Hospital of Ioannina (2005–2013).
  2. As a Consultant Lipidologist at the Addenbrooke's Hospital Lipid Clinic (2016–present).

I joined Addenbrooke's Hospital in 2014 as a Senior Clinical Fellow in the Clinical Pharmacology Unit. There, I continued research and developed my expertise in Hypertension.

In 2016, I became a Consultant in Acute Medicine, leading the medical take in the department. My post includes a secondment to the GSK Clinical Unit Cambridge.

I trained as a First in Human Phase 1 Clinical Trials PI through the Diploma in Human Pharmacology. I passed the exam and was awarded the Diploma in Human Pharmacology (DHP) in 2018. The DHP is MHRA-accredited for conducting First in Human Phase 1 Clinical Trials as a PI. At GSK’s Early Phase Clinical Trials Unit, I lead the design and conduct of Early Phase trials and Experimental Medicine studies. I also join Expert Panels to identify new drug targets in Metabolic Medicine.

I maintain international collaborations with European universities and academics.

Membership / accreditations

  • Fellow of the Royal College of Physicians (FRCP)
  • Fellow of the Faculty of Pharmaceutical Medicine (FFPM)
  • MHRA-accreditation as Principal Investigator for Phase 1 First in Human Clinical Trials (Diploma in Human Pharmacology)
  • Fellow of the Royal Society for Public Health (FRSPH)
  • Member of the Hellenic and European Atherosclerosis Societies

Personal interests

  • Literature
  • Arts
  • Music