Long Synacthen test: to assess the production of cortisol

Information for parents/carers

Background

Hormones are natural chemicals which are produced by the body. One of the hormones produced in the body by the adrenal glands is called cortisol. This is an important hormone as too little or too much of it can cause the body to be unable to respond to stresses such as infection, injury, illness and trauma. Cortisol levels in the body vary greatly throughout the day and can be difficult to measure. This test will stimulate the body to release cortisol using a medicine called Synacthen, so that the amounts produced can be accurately measured.

During the test

Your child can eat and drink normally prior to and throughout the test. On arrival at the Weston Centre, the doctor or nurse will discuss the test with you and give you the opportunity to ask questions. You should expect to be at the clinic for approximately one hour. The local anaesthetic cream you have been supplied with will help to numb the skin before the blood tests are taken. Synacthen is given as an injection into either your child’s bottom or the top of your child’s leg. Your child will be able to go home once the injection is completed but a further two injections will be necessary, one on day two and one on day three. Blood tests will also be taken on both these days and a final set on day four.

Effects of Synacthen

Most children experience no effects from the test but very rarely a child may have an allergic reaction, for example rash, nausea, dizziness breathing difficulties or swelling which would be treated immediately.

Follow-up

At your follow-up appointment you will have the opportunity to discuss the blood results with the doctor and whether any further treatment or tests are necessary.

Contacts

Please do ask the doctors any questions you may have or contact the specialist endocrine nurses on 01223 217496.