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Penile cancer

Penile cancer (cancer of the penis) is a rare cancer that starts when the abnormal cells begin to divide and grow in an uncontrolled way. It can develop anywhere on the penis but it mostly affects the skin of the penis and the foreskin, which covers the head of the penis.

The penis is the male reproductive organ responsible for urination and sexual intercourse. It contains a tube called the urethra, which carries semen (sperm) from the testicles and urine (pee) from the bladder out of the body.

Diagram of the male reproductive organs, labelled: bladder, seminal vesicles, prostate, urethra, penis, epididymis, rectum, anus, vas deferens, testis, scrotum

Signs and symptoms of penile cancer include:

  • a growth, lump or sore (ulcer) anywhere on the penis
  • thickening or raised areas anywhere on the penis
  • changes in the colour of the skin or the foreskin, such as redness or white patches
  • bleeding or foul-smelling discharge from the penis
  • a lump, pain, bleeding or discharge from underneath the foreskin

The most common type of penile cancer is the squamous cell carcinoma, which originates in the outer layer of the skin (epithelium).

Rarer types of cancer that can affect the penis include:

  • melanoma
  • basal cell carcinoma (BCC)
  • adenocarcinoma
  • urothelial carcinoma
  • sarcoma

Treatment for penile cancer

The treatment you have depends on several factors, which include:

  • the type and size of the cancer
  • the stage of the cancer
  • your age
  • your general health

Once the diagnosis of penile cancer is confimed at CUH, patients are referred to Norfolk and Norwich University Hospitals NHS Foundation Trust (NNUH) for further review and management. NNUH is a specialist centre for the East of England.

You, along with your clinician at NNUH, will then discuss your treatment recommendations at the clinic appointment and decide on the right treatment plan for you. Your clinician will explain the different treatment options and possible side effects.

The treatment for penile cancer can include:

  • surgery
  • chemotherapy creams
  • laser treatment
  • cryotherapy
  • chemotherapy
  • radiotherapy
  • clinical trials

At times, you may require more than one treatment or a combination of different treatments to give the best chance of long-term cure and to help reduce the risk of the cancer coming back.

Read more about the different types of treatment on our website.

Resources and support

Our teams

Our uro-oncology team includes specialists from different areas, who work together to support you.

You will receive contact details for your clinical team at your clinic consultation.

Learn more about urology.

Treatment location

To receive your diagnosis at CUH, you may be seen in one of our urology outpatient clinics, Clinic 4a, which sees patients with urological conditions.

For treatment, such as chemotherapy or radiotherapy, you will likely attend the Norfolk and Norwich University Hospitals NHS Foundation Trust (NNUH) oncology services. The instructions will be provided to you by the NNUH team.

Find more about urology services.