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Prof Ravi Gupta included in 2020 TIME100 list

A head and shoulders picture of Professor Ravi Gupta smiling
Prof Ravi Gupta

Addenbrooke’s infectious disease consultant and Cambridge University Professor Ravi Gupta is named in this year’s TIME magazine 100 list of the world's most influential people. He said:

It is a huge and unexpected honour to be included in this year’s TIME 100 list of influential individuals worldwide.

Prof Ravi Gupta

This accolade is in recognition of work on the London Patient, Adam Castillejo, in whom we demonstrated cure of HIV infection by stem cell transplantation, the second such case in history.

"This was an incredible journey spanning multiple countries over five years. Now, with over a decade working in HIV virology, my team has been able to draw on this experience to fight Covid-19 on multiple fronts, from testing to understanding why people become so sick.

Prof Ravi Gupta explains his work at CUH and CITIID

Link: https://www.youtube.com/watch?v=ijHt483oBMQ&feature=emb_title

Video transcript

00:00:09:19 - 00:00:10:14

Hi, I'm Ravi,

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I study

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infectious diseases

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Addenbrooke’s hospital

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and the University of Cambridge.

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I've always been interested

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in pushing boundaries

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and extending the reaches

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of our knowledge.

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In the hospital setting,

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that's about discovering

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new tests, treatments

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and even cures for patients.

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At the university, scientists

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work alongside medics at Addenbrooke's

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to bring research

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from the bench

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to bedside, thereby saving lives.

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When Covid-19 hit,

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all of us

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working in life

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sciences shifted overnight

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to combat this new threat.

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Everything I'd learned

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in a decade of studying

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HIV in sub-Saharan Africa and the UK

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was now relevant to fighting Covid-19.

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I'm very proud of the way

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we've worked together across the hospital

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and the university,

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developing new Covid

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lab tests and scaling them up

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for use on the frontline

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with patients and staff,

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studying the genetics of the virus

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to track how it moves between people

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and understanding the basic biology

00:01:01:21 - 00:01:03:16

of severe Covid inflammation,

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so we can develop treatments for this.

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There's still so much more to do,

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we need an array of effective

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tests, vaccines

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and treatments

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which are accessible

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to people across the world.

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But I'm excited about the next few months

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because I know that these solutions

00:01:17:24 - 00:01:18:21

are within our grasp.

Since February this year, Prof Gupta and his team at the Cambridge Institute for Therapeutic Immunology and Infectious Diseases (CITIID) have been applying all their expertise to help diagnose and treat Covid, including developing a new rapid point-of-care test for Covid-19 using SAMBA II machines. These are currently in use at Addenbrooke’s and are crucial to providing a fast diagnosis in order to provide the best possible care for patients.

Dr Ashley Shaw, Medical Director at Cambridge University Hospitals (CUH), which runs Addenbrooke’s, said:

This is an incredible achievement, and all of us at CUH are very proud of Ravi.

Dr Ashley Shaw, Medical Director, CUH

We are delighted to have world-class researchers like him, and including many others, working in our hospital helping us save patients’ lives.

“Never has it been more important that clinicians work hand-in-hand with scientists. Ravi and his colleagues at Cambridge University have been alongside us from the very start of the Covid crisis making sure that scientific developments transfer from the lab bench to the patient’s bedside as quickly as humanly possible.”

A member of staff operating the SAMBA testing machine.
Staff member using the SAMBA testing machines

As well as his roles at Addenbrooke’s and Cambridge University, Prof Gupta holds a faculty position at the Africa Health Research Institute (AHRI) where his work is focussed on understanding the genetic and biological properties of drug resistant HIV in South Africa, where it is estimated that 10% or more patients experience treatment failure.