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First Covid-19 'booster' jabs given in new vaccine trial

Volunteers from Cambridgeshire are among the first to get a third 'booster' dose of a Covid-19 vaccine, as part of a new UK trial.

The Cov-Boost study will provide vital data on the immune response to a third dose of a Covid vaccine and could help shape a potential 'booster' jab programme this autumn.

The trial is being run by 18 research sites across the UK, including Addenbrooke's Hospital.

Professor Krishna Chatterjee, NIHR
Prof Krishna Chatterjee, Director of the NIHR Clinical Research Facility in Cambridge

We have conducted trials of several Covid-19 vaccine studies over the last year. It’s an exciting opportunity to now work on a study to determine the effects of a third ‘booster’ dose

Prof Krishna Chatterjee, Director of the NIHR Clinical Research Facility in Cambridge

Prof Krishna Chatterjee, Director of the NIHR Clinical Research Facility in Cambridge

Link: https://youtu.be/Q-wlJIH8f54

The trial in Cambridge will include several different Covid-19 vaccines including the Pfizer/BioNTech, Janssen and Valneva.

More than 180 participants from the Cambridgeshire area are taking part, with all volunteers aged 30 years or older and already double dosed with a Covid-19 vaccine.

One vaccine booster will be randomly allocated to each participant, including a placebo vaccine.

The study will monitor for any reaction and measure the immune response to the vaccination, by taking a series of blood tests from participants over the next year.

Cov-Boost Trial
Prof Peter Landshoff, Cambridge Cov-Boost volunteer

The government-funded trial, led by the University of Southampton, is being carried out by the National Institute for Health Research (NIHR) Cambridge Clinical Research Facility at Addenbrooke's Hospital.

Initial results are expected in September and will help inform any potential booster programme from autumn this year, ensuring the country’s most vulnerable are given the strongest possible protection over the winter period.

Volunteering for COVID-19 vaccine clinical trials

People wishing to volunteer to support clinical trials can sign up for information on Covid-19 vaccine trials with the NHS COVID-19 Vaccine Research Registry.

Anyone living in the UK can sign up online to take part in the trials through the NHS, giving permission for researchers to contact you if they think you’re a good fit.

Once you sign up, you can withdraw at any time and request that your details be removed from the COVID-19 Vaccine Research Registry.

The process takes about 5 minutes to complete.

To volunteer for the Cov-Boost trial, follow this link;

https://www.covboost.org.uk/home