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Research and clinical trials

Research is fully integrated into cancer care in our hospital to constantly seek to improve outcomes for our patients. The Cancer Directorate is the clinical hub of the CRUK Cambridge Centre encompassing multiple clinical, translational and basic scientific research groups based around Cambridge, with a shared goal of transforming scientific discoveries into clinical benefit.  In the Cancer Directorate, over 40 senior consultant oncologists and haematologists, work with academic and industry colleagues within the 12 work programmes established by the CRUK Cambridge Centre, offering patients access to the latest research into treatment, early diagnosis and prevention of cancer.  We are recognised as national and global leaders in research, teaching and training.

In the last research assessment exercise, which is the way that the government assesses research programmes for funding, 80% of our research was graded as 'world leading' or 'internationally excellent'. Cancer research is a major theme in the National Institute for Health Research (NIHR) Cambridge Biomedical Research Centre, one of only 5 such centres in the UK.  We are also one of 6 leading cancer centres which make up Cancer Core Europe, a unique international partnership.

New treatments for cancer are being developed very rapidly and our service has over 160 different clinical trials available at any one time evaluating new treatments across all cancer types. We conduct both early and late phase studies. Cambridge is one of 17 national Experimental Cancer Medicine Centres. In 2016, Addenbrooke’s Hospital recruited the highest number of cancer patients to NIHR portfolio clinical trials compared with all other trusts across the country.

The Cambridge Cancer Trials Centre (CCTC) is the cancer theme of the nationally accredited Cambridge Clinical Trials Unit. The CCTC collaborates with a large number of senior oncologists who lead national and international academic clinical trials, many of which frequently stem from local scientific discoveries. The CCTC coordinates and supports the clinical and translational work of the CRUK Cambridge Centre.  To do so, it employs statisticians, programmers and trial managers, as well as research nurses/practitioners, data managers and other staff to assist in the conduct of patient-based research, who  are based in S4 and Coton House at Addenbrooke’s.