Breathlessness research

Pre-clinical phase:

Booth S, Silvester S, Todd C (2003). Breathlessness in cancer and chronic obstructive pulmonary disease: using a qualitative approach to describe the experience of patients and carers. Palliative and Supportive Care 1 (4):337-344.

Phase I:

Booth S, Farquhar M, Gysels M, Bausewein C, Higginson IJ (2006) The impact of a breathlessness intervention service (BIS) on the lives of patients with intractable dyspnoea: a qualitative Phase I study.  Journal of Palliative and Supportive Care 4: 287-293.

Phase II:

Farquhar M, Higginson IJ, Fagan P, Booth S. The feasibility of a single-blinded fast-track pragmatic randomised controlled trial of a complex intervention for breathlessness in advanced disease. BMC Palliative Care 2009; 8:9.

Farquhar MC, Higginson IJ, Fagan P, Booth S. Results of a pilot investigation into a complex intervention for breathlessness in advanced chronic obstructive pulmonary disease (COPD): brief report.  Palliative and Supportive Care 2009; 8 (2) (in press).

Farquhar M, Ewing G, Higginson IJ, Booth S. The experience of using the SEIQoL-DW with patients with advanced chronic obstructive pulmonary disease (COPD): issues of process and outcome. Quality of Life Research 2010 (in press).

Phase III:

Booth S, Moffat C, Farquhar M, Higginson IJ, Bausewein C, Burkin J. Developing a breathlessness service for patients with palliative and supportive care needs, irrespective of diagnosis. Journal of Palliative Care 2011;27(1): 28-36.

Farquhar M, Prevost AT, McCrone P, Higginson IJ, Gray J, Brafman-Kennedy B, Booth S. Study Protocol: Phase III single-blinded fast-track pragmatic randomised controlled trial of a complex intervention for breathlessness in advanced disease. Trials 2011, 12:130.

Related papers by members of research team:

Booth S (2006). Improving research methodology in breathlessness: a meeting convened by the MRC Clinical Trials Unit and the Cicely Saunders Foundation. Palliative Medicine 20 (3):219-220.

Bausewein C, Malik F, Booth S, Higginson IJ (2007). Recent developments in managing breathlessness: International researchers' meeting on Breathlessness in London, November 2006. Progress in Palliative Care 15:279-284.

Bausewein C, Farquhar M, Booth S, Gysels M, Higginson IJ (2007) Measurement of breathlessness in advanced disease: a systematic review. Respiratory Medicine 101 (3): 399-410.

Bausewein C, Booth S, Gysels M, Higginson IJ (2008) Non-pharmacological interventions for breathlessness in advanced stages of malignant and non-malignant diseases (review). Cochrane Database of Systematic Reviews 2008, Issue 2.

Farquhar M, Higginson IJ, Booth S. Repeated measurement of quality of life in palliative care research:  the experience of using the SEIQoL-DW in a pilot phase II RCT of a complex intervention for breathlessness (PCC conference abstract) Palliative Medicine 2008; 22 (4): 596.

Farquhar M, Higginson IJ, Booth S (2009).  Fast-Track Trials in Palliative Care: An Alternative Randomized Controlled Trial Design. Journal of Palliative Medicine 12 (3): 213

Dorman S, Jolley C, Abernethy A, Currow D, Johnson M, Farquhar M, Griffiths G, Peel T, Moosavi S, Byrne A, Wilcock A, Alloway  L, Bausewein C, Higginson I, Booth S.  Researching breathlessness in palliative care: consensus statement of the National Cancer Research Institute Palliative Care Breathlessness Subgroup. Palliative Medicine 2009; 23: 213-227.

Rocker G, Horton R, Currow D, Goodridge D, Young J, Booth S. Palliation of dyspnoea in advanced COPD: revisiting a role for opioids. Thorax 2009;64;910-5.

Gray J. E. A., Booth S., Brage S., Yorke J., Moosavi S., Bausewein C., Molasiotis A., Johnson M., and Farquhar M., (2010) BRIG Progress in Palliative Care, 18 (I2 ); 95-98

Booth S, Moosavi SH, Higginson IJ. The etiology and management of intractable breathlessness in patients with advanced cancer: a systematic review of pharmacological therapy. Nature Clinical Practice Oncology 2008; 5(2): 90-100.

Galbraith S, Fagan P, Perkins P, Lynch A, Booth S. Does the use of a handheld fan improve chronic dyspnea? A randomized, controlled, crossover trial. Journal of Pain & Symptom Management 2010; 39 (5):831-838.

Bausewein C, Booth S, Gysels M, Ku¨hnbach R, Haberland B, Higginson IJ. Understanding Breathlessness: Cross-Sectional Comparison of Symptom Burden and Palliative Care Needs in Chronic Obstructive Pulmonary Disease and Cancer. Journal of Palliative Medicine 2010; 13 (9): 1109-1118.